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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1662464Generated: October 29, 2026

Pyrrolidine → Methyl 2'-fluoro-5'-(methyloxy)-2-(1-pyrrolidinylmethyl)-1,1'-biphenyl-4-carboxylate

https://huagongshe.com/reaction/1662464

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantMethyl 2'-fluoro-5'-(methyloxy)-2-(1-piperidinylmethyl)-1,1'-biphenyl-4-carboxylateHCID 57705872—
ProductMethyl 2'-fluoro-5'-(methyloxy)-2-(1-pyrrolidinylmethyl)-1,1'-biphenyl-4-carboxylateHCID 57705589—

Reaction Steps

Compound 66.65A was synthesized using a procedure analogous to that used for 66.64A using pyrrolidine in place of piperidine. MS ESI (pos.) m/e: 344 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08030354B2
Source datasetuspto-grants-2011_10
ORD IDord-ac5e085b30a9405484a5cdd988bc70ea
Source noteuspto-grants-2011_10