反应详情

温度

70 °C

A mixture of 66.69A (0.094 g, 0.30 mmol), 2,6-dimethylpiperidine (0.069 g, 0.61 mmol) (commercially available from Aldrich) and cesium carbonate (0.20 g, 0.61 mmol) in DMSO (4 mL) was stirred at 70° C. for 24 hours. The product was purified by reverse phase HPLC to give 66.69B in 30% yield.

1. customThe product was purified by reverse phase HPLC