反应详情

LAH (1.0 M solution in THF) (0.086 mL, 0.086 mmol) was added slowly to a solution of 66.71A (0.032 g, 0.086 mmol) in THF (1.5 mL) and the mixture was stirred at room temperature for 33 minutes. The mixture was poured into brine (2 mL) and extracted with EtOAc (3×30 mL). The combined organic phase was dried over anhydrous sodium sulfate and filtered. After removing solvent, 66.71B (29 mg) was obtained.

1. extractionextracted with EtOAc (3×30 mL)
2. dry with materialThe combined organic phase was dried over anhydrous sodium sulfate
3. filtrationfiltered
4. customAfter removing solvent