HRID1662476

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24386

Thionyl chloride

Cl2OS

结构：COc1ccc(F)c(-c2ccc(CO)cc2CN2[C@H](C)CC[C@H]2C)c1

HCID57706802

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(F)c(-c2ccc(CCl)cc2CN2[C@H](C)CC[C@H]2C)c1

HCID57705528

未命名化合物

收率 92.1%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Thionyl chloride (0.25 g, 2.1 mmol) was added to a solution of 66.71B (0.029 g, 0.084 mmol) in DCM (0.7 mL) and the mixture was stirred at room temperature for 1 hour. After removing solvent, 66.71C (28 mg) was obtained.

WORKUP

后处理

customAfter removing solvent