反应详情

To a solution of 102.B (mixture of geometric isomers) (0.11 g, 0.35 mmol) in EtOAc (2 mL) was added Pd/C (10 wt. %) (0.019 g, 0.018 mmol) under N2. The mixture was purged with H2, stirred overnight under a H2 balloon, filtered through silica gel (EtOAc), and concentrated. The crude product was purified by silica gel flash chromatography (10-40% EtOAc/hexane) to afford 102.C (0.060 g, 76%) as a pale yellow oil.

1. customThe mixture was purged with H2
2. filtrationfiltered through silica gel (EtOAc)
3. concentrationconcentrated
4. customThe crude product was purified by silica gel flash chromatography (10-40% EtOAc/hexane)