(4R)-1-(3-benzyl-5-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-fluoro-N,N-dimethyl-L-prolinam ide → (4R)-1-(3-benzyl-5-chloro-1-{[4-methoxy-2-(trifluoromethoxy)phenyl]sulfonyl}-2-oxo-2,3-dihy dro-1H-indol-3-yl)-4-fluoro-N,N-dimethyl-L-prolinamide

Participants

Reaction Steps

With 87 mg of the compound obtained in Step 30-2 and of 74 mg 4-methoxy-2-(trifluoromethoxy)benzene sulfonyl chloride as starting materials, 67 mg of the title compound (colorless solid) was obtained by a similar method to Example 2.

Provenance & Evidence