HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-methylanisole → 5-bromo-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-methylanisole | HCID 89143 | — |
| Reactant | 5-Bromo-1H-pyrrolo[2,3-b]pyridine-2,3-dione | HCID 53302025 | — |
| Product | 5-bromo-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one | HCID 67428555 | 58.5% |
Reaction Steps
With 2.00 g of the compound obtained in Step 120-3 and 2.26 g of 3-bromo-4-methoxy toluene as starting materials, 1.80 g of the title compound was obtained by a similar method to Step 21-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-f48aec5d3b9949e8af9c51ac86ef86db |
| Source note | uspto-grants-2011_10 |