5-chloro-1H-indole-2,3-dione → HCID 67428654, compound

HRID 1662735Notes

Reaction equation

HRID 1662735 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[N:5]([CH3:7])[CH3:6].[Cl:13][C:14]1[CH:15]=[C:16]2[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=[O:23])[C:17]2=[O:24]>>[Cl:13][C:14]1[CH:15]=[C:16]2[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=[O:23])[C:17]2([C:2]1[CH:3]=[C:4]([N:5]([CH3:7])[CH3:6])[CH:8]=[CH:9][C:10]=1[O:11][CH3:12])[OH:24]

Participants

3

Reactant 2

HCID 872035-chloro-1H-indole-2,3-dioneHCID 713327633-Bromo-4-methoxy-N,N-dimethylaniline

Product 1

HCID 67428654HCID 67428654, compoundYield 80.2%

Procedure

With 500 mg of the compound obtained in Step 190-2 and 270 mg of 5-chloroisatin as starting materials, 397 mg of the title compound (brown solid) was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record
ord-bd0e5f2623004a6d879bde82e2892e09
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

Loading…