5-chloro-1H-indole-2,3-dione → HCID 67428429, compound

HRID 1662742Notes

Reaction equation

HRID 1662742 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH2:10][N:11]([CH3:13])[CH3:12])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[Cl:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[NH:20][C:19](=[O:24])[C:18]2=[O:25]>>[Cl:14][C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[NH:20][C:19](=[O:24])[C:18]2([C:2]1[CH:3]=[C:4]([CH2:10][N:11]([CH3:13])[CH3:12])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9])[OH:25]

Participants

3

Reactant 2

HCID 872035-chloro-1H-indole-2,3-dioneHCID 204305213-Bromo-4-methoxy-N,N-dimethylbenzenemethanamine

Product 1

HCID 67428429HCID 67428429, compoundYield 26.9%

Procedure

With 2.00 g of the compound obtained in Step 195-1 and 1.24 g of 5-chloroisatin as starting material, 637 mg of the title compound (pale red solid) was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record
ord-feb61abe990149279cf552c21444b2be
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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