HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59867958, compound → HCID 86625716, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59867958 | HCID 59867958 | — |
| Reactant | (4R)-4-hydroxy-N,N-dimethyl-L-prolinamide trifluoroacetate | HCID 67429482 | — |
| Reactant | 3-(3,5-dichloro-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-methoxy benzaldehyde | HCID 86625717 | — |
| Product | HCID 86625716 | HCID 86625716 | — |
Reaction Steps
With 26.3 g of the compound obtained in Step 198-1 and (4R)-4-hydroxy-N,N-dimethyl-L-prolinamide trifluoroacetate (35.1 mmol) as starting materials, 12.5 g of a diastereoisomer mixture of the title compound (colorless amorphous) was obtained by a similar method to Step 4-2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-00ac955e659748638112eb533efb2ac7 |
| Source note | uspto-grants-2011_10 |