HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → (4R)-1-(5-chloro-3-{5-[(diethylamino)methyl]-2-methoxyphenyl}-1-{[4-methoxy-2-(trifluorome thoxy)phenyl]sulfonyl}-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-L-prolinami de
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | HCID 59867892 | HCID 59867892 | — |
| Product | (4R)-1-(5-chloro-3-{5-[(diethylamino)methyl]-2-methoxyphenyl}-1-{[4-methoxy-2-(trifluorome thoxy)phenyl]sulfonyl}-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-L-prolinami de | HCID 59867904 | — |
Reaction Steps
With 101 mg of the compound obtained in Step 204-7 and diethyl amine (18 μl) as starting material, 31.0 mg of the title compound (colorless amorphous) was obtained by a similar method to Step 195-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08030499B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-35d8c1f8a91c4cca997dd0b458681fa6 |
| Source note | uspto-grants-2011_10 |