Benzene, 2-bromo-1,4-dimethyl- → HCID 67427804, compound

HRID 1662777Notes

Reaction equation

HRID 1662777 reaction equation
Br[C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH3:9].[Cl:10][C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]2=[O:21]>>[Cl:10][C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]2([C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH3:9])[OH:21]

Participants

3

Reactant 2

HCID 11121Benzene, 2-bromo-1,4-dimethyl-HCID 872035-chloro-1H-indole-2,3-dione

Product 1

HCID 67427804HCID 67427804, compoundYield 88.8%

Procedure

With 8.00 g of 1-bromo-2,5-dimethyl benzene and 5.79 g of 5-chloroisatin as starting materials, 8.15 g of the title compound (colorless amorphous) was obtained by a similar method to Step 21-1.

Sources & evidence

ORD record
ord-17592a8e97184b8ebd039896df421d8d
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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