4-Methoxybiphenyl → HCID 67429460, compound

HRID 1662779Notes

Reaction equation

HRID 1662779 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:5][CH:4]=1.[Cl:15][C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[NH:21][C:20](=[O:25])[C:19]2=[O:26]>>[Cl:15][C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[NH:21][C:20](=[O:25])[C:19]2([OH:26])[C:4]1[CH:5]=[C:6]([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:7]=[CH:8][C:3]=1[O:2][CH3:1]

Participants

3

Reactant 2

HCID 119434-MethoxybiphenylHCID 872035-chloro-1H-indole-2,3-dione

Product 1

HCID 67429460HCID 67429460, compoundYield 50%

Procedure

With 18.4 g of 4-methoxybiphenyl and 15.1 g of 5-chloroisatin as starting materials, 15.2 g of the title compound (yellow solid) was obtained by a similar method to Step 245-1.

Sources & evidence

ORD record
ord-9383a541e62f4c92a87adc2f0200618f
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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