3-Methoxytoluene → HCID 67429065, compound

HRID 1662783Notes

Reaction equation

HRID 1662783 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH3:9])[CH:6]=[CH:7][CH:8]=1.[Cl:10][C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]2=[O:21]>>[Cl:10][C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]2([OH:21])[C:8]1[CH:7]=[CH:6][C:5]([CH3:9])=[CH:4][C:3]=1[O:2][CH3:1]

Participants

3

Reactant 2

HCID 75303-MethoxytolueneHCID 872035-chloro-1H-indole-2,3-dione

Product 1

HCID 67429065HCID 67429065, compoundYield 12.6%

Procedure

With 22.3 g of 3-methoxy toluene and 33.1 g of 5-chloroisatin as starting materials, 6.98 g of the title compound (colorless solid) was obtained by a similar method to Step 239-1.

Sources & evidence

ORD record
ord-2c67fd14241e4e1e9780918877bf9d09
Source dataset
uspto-grants-2011_10
Patent number
US08030499B2

Reaction notes

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