HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → HCID 178508067, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Reactant | 3-Amino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one--hydrogen chloride (1/1) | HCID 67435771 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178508067 | HCID 178508067 | — |
Reaction Steps
0.57 g of 2-aminothiazole is solubilized in 3 ml of 6N hydrochloric acid. The medium is cooled to zero degrees, and then a solution of 0.39 g of sodium nitrite in 3 ml of water is added over 3 minutes. The medium is then kept stirring for 10 minutes between 0 and 5° C. A mixture of 1 g of 3-amino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one hydrochloride, 5 ml of ethanol, 5 ml of water and 1.7 g of sodium acetate is added to the reaction medium.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034124B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-4a8c1dd8d6ce45bb9065e332ff929e23 |
| Source note | uspto-grants-2011_10 |