HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidineethanol → HCID 21096917, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidineethanol | HCID 73953 | — |
| Reactant | 3-Chloroisoquinoline | HCID 640968 | — |
| Product | HCID 21096917 | HCID 21096917 | 21.7% |
Reaction Steps
The process is performed as described in Example 4 (step 4.1). Starting with 1 g (6.11 mmol) of 3-chloroisoquinoline and 0.869 g (6.72 mmol) of 2-(4-piperidyl)ethanol, and after chromatography on silica gel, eluting with a 98/2 mixture of dichloromethane and methanol, 0.34 g of pure product is obtained in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034818B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-501a1c6d3fc84cb0b71a28128fd641ce |
| Source note | uspto-grants-2011_10 |