3-Azaisatoic anhydride → 1-(6-Oxo-1,6-dihydro-pyridin-3-ylmethyl)-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione

Participants

Reaction Steps

May be prepared by a similar procedure as described for preparation 7B, starting from 1H-pyrido[2,3-d][1,3]oxazine-2,4-dione (can be prepared as described by Beckwith and Hickman in J. Chem. Soc. (C), 1968 pp 2756-2759) and 5-hydroxymethyl-1H-pyridin-2-one (prepared as described in WO 01/77078 A1).

Provenance & Evidence