N-Hydroxyphthalimide → 854382-42-6

HRID 1663103Notes

Reaction equation

HRID 1663103 reaction equation
[OH:1][N:2]1C(=O)C2=CC=CC=C2C1=O.[CH3:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18]Br)=[CH:16][C:15]=1[C:22]([F:25])([F:24])[F:23]>>[CH3:13][C:14]1[CH:21]=[CH:20][C:17]([CH2:18][O:1][NH2:2])=[CH:16][C:15]=1[C:22]([F:25])([F:24])[F:23]

Participants

3

Reactant 2

HCID 10665N-HydroxyphthalimideHCID 27756274-Methyl-3-(trifluoromethyl)benzyl bromide

Product 1

HCID 25137647854382-42-6

Procedure

Prepared by a similar procedure as described for preparation 15, starting from N-hydroxyphthalimide and 4-methyl-3-(trifluoromethyl)benzyl bromide (JRD fluorochemicals). 13C-NMR (CDCl3) δ 136.4, 135.5, 132.1, 131.5, 129.0, 125.8, 124.5, 77.0, 19.1.

Workup

  1. customPrepared by a similar procedure
  2. customas described for preparation 15

Sources & evidence

ORD record
ord-2b247472470f42f4999fdc78c7e12f02
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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