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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1663113Generated: October 28, 2026

N-Hydroxyphthalimide → O-(2,6-Dichloro-pyridin-4-ylmethyl)-hydroxylamine hydrochloride

https://huagongshe.com/reaction/1663113

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-HydroxyphthalimideHCID 10665—
Reactant4-(Bromomethyl)-2,6-dichloropyridineHCID 2781829—
ProductO-(2,6-Dichloro-pyridin-4-ylmethyl)-hydroxylamine hydrochlorideHCID 86615646—

Reaction Steps

Prepared by a similar procedure as described for preparation 18. Starting materials: N-hydroxyphthalimide and 4-bromomethyl-2,6-dichloropyridin (Maybridge). 1H-NMR (DMSO-d6) δ 11.2 (br, 3H), 7.62 (s, 2H), 5.18 (s, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08034811B2
Source datasetuspto-grants-2011_10
ORD IDord-ed5e4705eefd45daba55b4a84794e02a
Source noteuspto-grants-2011_10