N-Hydroxyphthalimide → O-(2-Phenyl-thiazol-4-ylmethyl)-hydroxylamine hydrochloride

HRID 1663116Notes

Reaction equation

HRID 1663116 reaction equation
[OH:1][N:2]1C(=O)C2=CC=CC=C2C1=O.Cl.[Cl:14][CH2:15][C:16]1[N:17]=[C:18]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[S:19][CH:20]=1>>[ClH:14].[C:21]1([C:18]2[S:19][CH:20]=[C:16]([CH2:15][O:1][NH2:2])[N:17]=2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 10665N-HydroxyphthalimideHCID 162436754-(Chloromethyl)-2-phenyl-1,3-thiazole hydrochloride

Product 1

HCID 67132053O-(2-Phenyl-thiazol-4-ylmethyl)-hydroxylamine hydrochloride

Procedure

Prepared by a similar procedure as described for preparation 12, starting from N-hydroxyphthalimide and 4-chloromethyl-2-phenyl-thiazole hydrochloride.

Workup

  1. customPrepared by a similar procedure
  2. customas described for preparation 12

Sources & evidence

ORD record
ord-6c9394c052064796ae2ac6cf37d9e15f
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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