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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1663120Generated: October 28, 2026

N-Hydroxyphthalimide → O-(5-Chloro-thiophen-2-ylmethyl)-hydroxylamine

https://huagongshe.com/reaction/1663120

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-HydroxyphthalimideHCID 10665—
Reactant2-Chloro-5-(chloromethyl)thiopheneHCID 583079—
ProductO-(5-Chloro-thiophen-2-ylmethyl)-hydroxylamineHCID 10986580—

Reaction Steps

Prepared by a similar procedure as described for preparation 15. Starting materials: N-hydroxyphthalimide and 2-chloro-5-(chloromethyl)thiophene (Aldrich). 13C-NMR (DMSO-d6) δ 140.2, 127.9, 126.3, 126.0, 71.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08034811B2
Source datasetuspto-grants-2011_10
ORD IDord-03d2ae0217664db097dda48cb400b540
Source noteuspto-grants-2011_10