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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1663135Generated: October 28, 2026

5-Ethynyl-1-methyl-1H-imidazole → N-[3-(3-Methyl-3H-imidazol-4-ylethynyl)-benzyloxy]-2-[(pyridin-4-ylmethyl)-amino]-benzamide

https://huagongshe.com/reaction/1663135

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Ethynyl-1-methyl-1H-imidazoleHCID 3333106—
ReactantN-(3-Iodo-benzyloxy)-2-[(pyridin-4-ylmethyl)-amino]-benzamideHCID 58989772—
ProductN-[3-(3-Methyl-3H-imidazol-4-ylethynyl)-benzyloxy]-2-[(pyridin-4-ylmethyl)-amino]-benzamideHCID 11750954—

Reaction Steps

Starring materials: N-(3-Iodo-benzyloxy)-2-[(pyridin-4-ylmethyl)-amino]-benzamide (see Example 361) and 5-ethynyl-1-methyl-1-H-imidazole (Aldrich).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08034811B2
Source datasetuspto-grants-2011_10
ORD IDord-2a325dffa4d944ffabaccc9b08e02da8
Source noteuspto-grants-2011_10