N,N-Dimethylethylenediamine → HCID 58990006, compound

HRID 1663144Notes

Reaction equation

HRID 1663144 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][NH:8][C:9]2[CH:28]=[CH:27][CH:26]=[CH:25][C:10]=2[C:11]([NH:13][O:14][CH2:15][C:16]2[CH:17]=[C:18]([CH:22]=[CH:23][CH:24]=2)[C:19](O)=[O:20])=[O:12])=[CH:3][CH:2]=1.[CH3:29][N:30]([CH3:34])[CH2:31][CH2:32][NH2:33]>>[CH3:29][N:30]([CH3:34])[CH2:31][CH2:32][NH:33][C:19]([C:18]1[CH:17]=[C:16]([CH:24]=[CH:23][CH:22]=1)[CH2:15][O:14][NH:13][C:11](=[O:12])[C:10]1[CH:25]=[CH:26][CH:27]=[CH:28][C:9]=1[NH:8][CH2:7][C:4]1[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=1)=[O:20]

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 58989917HCID 58989917, compound

Product 1

HCID 58990006HCID 58990006, compound

Procedure

Prepared by a similar procedure as described for preparation of Example 405. Starting materials: 3-{2-[(Pyridin-4-ylmethyl)-amino]-benzoylaminooxymethyl}-benzoic acid (see Example 403) and 2-dimethylaminoethylamine. 13C-NMR (DMSO-d6) δ 165.8, 149.5, 148.9, 148.2, 136.1, 134.6, 132.4, 131.4, 128.2, 128.0, 127.7, 126.8, 121.9, 114.8, 113.3, 111.4, 76.5, 58.1, 45.2, 44.8, 37.3.

Workup

  1. customPrepared by a similar procedure
  2. customas described for preparation of Example 405

Sources & evidence

ORD record
ord-ab04f766ff2846eba04d9d91c08aca14
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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