3-Amino-1-propanol → HCID 58990033, compound

HRID 1663161Notes

Reaction equation

HRID 1663161 reaction equation
[CH:1]1([CH2:6][O:7][NH:8][C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[NH:17][CH2:18][C:19]2[CH:20]=[CH:21][C:22]([F:28])=[C:23]([CH:27]=2)[C:24](O)=[O:25])=[O:10])[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:29][CH2:30][CH2:31][CH2:32][OH:33]>>[CH:1]1([CH2:6][O:7][NH:8][C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[NH:17][CH2:18][C:19]2[CH:20]=[CH:21][C:22]([F:28])=[C:23]([CH:27]=2)[C:24]([NH:29][CH2:30][CH2:31][CH2:32][OH:33])=[O:25])=[O:10])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 90863-Amino-1-propanolHCID 58989765HCID 58989765, compound

Product 1

HCID 58990033HCID 58990033, compound

Procedure

Prepared by a similar procedure as described for the preparation of Example 499, starting from 5-[(2-cyclopentylmethoxycarbamoyl-phenylamino)-methyl]-2-fluoro-benzoic acid (Example 496) and 3-amino-propan-1-ol.

Workup

  1. customPrepared by a similar procedure
  2. customas described for the preparation of Example 499

Sources & evidence

ORD record
ord-371d66e3e95f400d902b5ab5b988dc05
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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