1-Methylpiperazine → HCID 58989911, compound

HRID 1663162Notes

Reaction equation

HRID 1663162 reaction equation
[CH:1]1([CH2:6][O:7][NH:8][C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[NH:17][CH2:18][C:19]2[CH:20]=[CH:21][C:22]([F:28])=[C:23]([CH:27]=2)[C:24]([OH:26])=O)=[O:10])[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:29][N:30]1[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]1>>[CH:1]1([CH2:6][O:7][NH:8][C:9](=[O:10])[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[NH:17][CH2:18][C:19]2[CH:20]=[CH:21][C:22]([F:28])=[C:23]([C:24]([N:33]3[CH2:34][CH2:35][N:30]([CH3:29])[CH2:31][CH2:32]3)=[O:26])[CH:27]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 58989765HCID 58989765, compound

Product 1

HCID 58989911HCID 58989911, compound

Procedure

Prepared by a similar procedure as described for the preparation of Example 499, starting from 5-[(2-cyclopentylmethoxycarbamoyl-phenylamino)-methyl]-2-fluoro-benzoic acid (Example 496) and 1-methyl-piperazine.

Workup

  1. customPrepared by a similar procedure
  2. customas described for the preparation of Example 499

Sources & evidence

ORD record
ord-c322eba495d948f1b13b79b261f0a496
Source dataset
uspto-grants-2011_10
Patent number
US08034811B2

Reaction notes

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