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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1663272Generated: October 31, 2026

Ethyl cyanoacetate → Ethyl 2-aminothiophene-3-carboxylate

https://huagongshe.com/reaction/1663272

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl cyanoacetateHCID 7764—
Reactant2-Aminothiophene-3-carbonitrileHCID 736607—
ProductEthyl 2-aminothiophene-3-carboxylateHCID 1988156—

Reaction Steps

The same procedure as 2-aminothiophene-3-carbonitrile was used except replacing malononitrile with ethyl cyano acetate. 1H-NMR (CDCl3, 400 MHz): 6.95, 6.15, 4.26, 1.32.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08034895B2
Source datasetuspto-grants-2011_10
ORD IDord-ac8cab2f37b44f0188cf1777e6b2c6d2
Source noteuspto-grants-2011_10