HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86613655, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 67436302 | HCID 67436302 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | HCID 86613655 | HCID 86613655 | 198.3% |
Reaction Steps
To a solution of the compound obtained in Example 1 (64 mg) in water/methanol was added 6N HCl (21 μL) and the mixture was concentrated in vacuo to give (3R)-1[bis-(4-chlorophenyl)methyl]-3-[[4-(trifluoromethyloxy)benzoyl]amino]-pyrrolidine hydrochloride (68 mg, yield: 100%) as an amorphous powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034949B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-89a4e79ca7434a80a9f713b77d4da4d9 |
| Source note | uspto-grants-2011_10 |