HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 6-(3-aminophenoxy)-N-methylimidazo[1,2-b]pyridazine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | 6-iodo-N-methylimidazo[1,2-b]pyridazine-2-carboxamide | HCID 57441026 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6-(3-aminophenoxy)-N-methylimidazo[1,2-b]pyridazine-2-carboxamide | HCID 57505510 | 36% |
Reaction Steps
Using 6-iodo-N-methylimidazo[1,2-b]pyridazine-2-carboxamide (0.30 g, 0.99 mmol), N,N-dimethylformamide (3.0 mL), potassium carbonate (275 mg, 1.99 mmol) and 3-aminophenol (163 mg, 1.49 mmol) as starting materials and in the same manner as in Example 91, the title compound (0.10 g, 36%) was obtained as a dark brown powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08034812B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-03f40eef1d464a1ebf4d6d462effc2c5 |
| Source note | uspto-grants-2011_10 |