Pyrrolidone carboxylic acid → N-[1-[2-(2-hydroxyphenyl)-7-methylquinazolin-4-yl]pyrrolidin-3-yl]-5-oxopyrrolidine-2-carboxamide
Reaction equation
[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[Cl:42][CH2:43][Cl:44].[NH2:1][CH:2]1[CH2:3][N:4]([c:7]2[n:8][c:9](-[c:18]3[c:19]([OH:24])[cH:20][cH:21][cH:22][cH:23]3)[n:10][c:11]3[cH:12][c:13]([CH3:17])[cH:14][cH:15][c:16]23)[CH2:5][CH2:6]1.[O:32]=[C:33]1[CH2:34][CH2:35][CH:36]([C:38](=[O:39])[OH:40])[NH:37]1.[OH2:41]>>[NH:1]([CH:2]1[CH2:3][N:4]([c:7]2[n:8][c:9](-[c:18]3[c:19]([OH:24])[cH:20][cH:21][cH:22][cH:23]3)[n:10][c:11]3[cH:12][c:13]([CH3:17])[cH:14][cH:15][c:16]23)[CH2:5][CH2:6]1)[C:38]([CH:36]1[CH2:35][CH2:34][C:33](=[O:32])[NH:37]1)=[O:39]Participants
6
Sources & evidence
- ORD record
- ord-17a477f247b54cc3bf1a8db3bec112a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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