Phenyltrimethylammonium bromide dibromide → HCID 87152141, compound

HRID 1664099Notes

Reaction equation

HRID 1664099 reaction equation
[Br-:1].[Br-].[Br-].C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.[CH:34]([C:37]([C:39]1[CH:52]=[CH:51][C:42]2[O:43][C:44]([F:50])([F:49])[C:45]([F:48])([F:47])[O:46][C:41]=2[CH:40]=1)=[O:38])([CH3:36])[CH3:35]>O1CCCC1>[F:50][C:44]1([F:49])[O:43][C:42]2[CH:51]=[CH:52][C:39]([C:37]([C:34]([Br:1])([CH3:36])[CH3:35])=[O:38])=[CH:40][C:41]=2[O:46][C:45]1([F:48])[F:47]

Participants

4

Reactant 2

HCID 17977687Phenyltrimethylammonium bromide dibromideHCID 87152139HCID 87152139, compound

Product 1

HCID 87152141HCID 87152141, compoundYield 171%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

1.89 g of phenyltrimethylammonium tribromide was added to a mixture comprising 1.40 g of 2,2,3,3-tetrafluoro-1,4-benzodioxan-6-yl isopropyl ketone and 19.7 ml of tetrahydrofuran, followed by a reaction for two hours at room temperature. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to obtain 1.78 g of oily α-bromoisopropyl 2,2,3,3-tetrafluoro-1,4-benzodioxan-6-yl ketone.

Workup

  1. customfollowed by a reaction for two hours at room temperature
  2. filtrationThe reaction mixture was filtered
  3. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-608b6d36819d4a7492cfd9540d0fb176
Source dataset
uspto-grants-2011_10
Patent number
US08039420B2

Reaction notes

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