Hydrazine → HCID 178446164, compound

HRID 1664511Notes

Reaction equation

HRID 1664511 reaction equation
[CH2:1]([N:6]1[C:14]2[N:13]=[CH:12][NH:11][C:10]=2[C:9](=[O:15])[NH:8][C:7]1=S)[CH2:2][CH2:3][CH2:4][CH3:5].[NH2:17][NH2:18]>O>[CH2:1]([N:6]1[C:14]2[N:13]=[CH:12][NH:11][C:10]=2[C:9](=[O:15])[NH:8]/[C:7]/1=[N:17]\[NH2:18])[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 576002363-Pentyl-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one

Product 1

HCID 178446164HCID 178446164, compoundYield 79.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

3-Pentyl-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one (6.0 g, 16 mmol) was mixed with hydrazine (10 mL, 300 mmol) and water (10 mL). The mixture was heated at 100° C. for 8 h. The solid formed was filtered and washed with water to give the desired product (3.0 g, 78%). LCMS calculated for C10H17N6O (M+H): 237.1. found: 237.1.

Workup

  1. customThe solid formed
  2. filtrationwas filtered
  3. washwashed with water

Sources & evidence

ORD record
ord-b0ccd06793cd451cbb2c6afb4e10dbb9
Source dataset
uspto-grants-2011_10
Patent number
US08039478B2

Reaction notes

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