Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 8-cyclobutyl-3-pentyl-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one | HCID 57600241 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178446160 | HCID 178446160 | 38.6% |
Reaction Steps
The mixture of 8-cyclobutyl-3-pentyl-2-thioxo-1,2,3,7-tetrahydro-6H-purin-6-one (0.6 g, 2.0 mmol) in 20 M of hydrazine in water (20 mL) was stirred at 100° C. overnight. After cooling to room temperature, the solid formed was filtered and dried Cooled down, the solid was isolated to give yield the desired product (230 mg, 38.6%). LCMS calculated for C14H23N6O (M+H): 291.2. found: 291.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08039478B2 |
|---|
| Source dataset | uspto-grants-2011_10 |
|---|
| ORD ID | ord-396063735093497cbadbdcc54c57bac0 |
|---|
| Source note | uspto-grants-2011_10 |
|---|