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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1664643Generated: October 26, 2026

imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester → Carbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester cyclohexyl-(3-fluoro-phenyl)-methyl ester

https://huagongshe.com/reaction/1664643

Reaction equation

Participants

RoleNameHCIDCharge
Reactantimidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl esterHCID 59187189—
ReactantCyclohexyl (3-fluorophenyl)methanolHCID 60798262—
ProductCarbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester cyclohexyl-(3-fluoro-phenyl)-methyl esterHCID 86638970—

Reaction Steps

The desired product was prepared by reacting imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester with cyclohexyl-(3-fluoro-phenyl)-methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08039483B2
Source datasetuspto-grants-2011_10
ORD IDord-f32bf8a34d1240078a6b2980555c85ff
Source noteuspto-grants-2011_10