Hydrochloric Acid → HCID 59722661, compound

HRID 1664806Notes

Reaction equation

HRID 1664806 reaction equation
C[O:2][C:3]1[C:8]([CH:9]2[CH2:14][CH2:13][N:12](C(OC(C)(C)C)=O)[CH2:11][CH2:10]2)=[CH:7][CH:6]=[CH:5][N:4]=1.Cl>>[NH:12]1[CH2:13][CH2:14][CH:9]([C:8]2[C:3](=[O:2])[NH:4][CH:5]=[CH:6][CH:7]=2)[CH2:10][CH2:11]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 86620121HCID 86620121, compound

Product 1

HCID 59722661HCID 59722661, compound

Procedure

tert-Butyl 4-(2-methoxypyridin-3-yl)piperidine-1-carboxylate (204 mg, 0.70 mmol) was added to hydrochloric acid (6.0 M in water; 5.81 mL, 34.89 mmol). After 18 h, the reaction mixture was concentrated and dried under reduced pressure to give the title compound. MS 179.1 (M+1).

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customdried under reduced pressure

Sources & evidence

ORD record
ord-221406aed885431a89258488191fb27a
Source dataset
uspto-grants-2011_10
Patent number
US08039460B2

Reaction notes

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