HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1664832Generated: November 1, 2026
Hydrochloric Acid → 1-Ethoxy-4,4,4-trifluoro-1-oxobutan-2-aminium chloride
https://huagongshe.com/reaction/1664832
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-Amino-4,4,4-trifluorobutanoic acid | HCID 353083 | — |
| Product | 1-Ethoxy-4,4,4-trifluoro-1-oxobutan-2-aminium chloride | HCID 86620125 | — |
Reaction Steps
2-Amino-4,4,4-trifluorobutanoic acid (11.7 g, 52.8 mmol) was added to a saturated solution of HCl in ethanol (100 mL) and heated to 85° C. After 4 h, the mixture was allowed to cool to ambient temperature and concentrated. MS 186.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08039460B2 |
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| Source dataset | uspto-grants-2011_10 |
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| ORD ID | ord-f91b68616d844b5083f8bd3c80cea176 |
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| Source note | uspto-grants-2011_10 |
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