Hydrochloric Acid → 3834-43-3

HRID 1664832Notes

Reaction equation

HRID 1664832 reaction equation
[NH2:1][CH:2]([CH2:6][C:7]([F:10])([F:9])[F:8])[C:3]([OH:5])=[O:4].[ClH:11].[CH2:12](O)[CH3:13]>>[Cl-:11].[CH2:12]([O:4][C:3](=[O:5])[CH:2]([NH3+:1])[CH2:6][C:7]([F:10])([F:9])[F:8])[CH3:13]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 3530832-Amino-4,4,4-trifluorobutanoic acid

Product 1

HCID 866201253834-43-3

Conditions

Temperature
85 °C

Procedure

2-Amino-4,4,4-trifluorobutanoic acid (11.7 g, 52.8 mmol) was added to a saturated solution of HCl in ethanol (100 mL) and heated to 85° C. After 4 h, the mixture was allowed to cool to ambient temperature and concentrated. MS 186.0 (M+1).

Workup

  1. temperatureto cool to ambient temperature
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-f91b68616d844b5083f8bd3c80cea176
Source dataset
uspto-grants-2011_10
Patent number
US08039460B2

Reaction notes

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