Hydrochloric Acid → HCID 67440367, compound

Participants

Reaction Steps

Hydrochloric acid (4.0 M in dioxane; 3 mL, 12.0 mmol) was added to a solution of tert-butyl [(6S,9R)-6-(2,3-difluorophenyl)-3-(tetrahydrofuran-3-yl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepin-9-yl]carbamate (113 mg, 0.261 mmol) in 1,4-dioxane (3 mL). After 2.5 h, the reaction was concentrated to give the title compound as a bis hydrochloride salt (117 mg). MS 334.2 (M+1).

Provenance & Evidence