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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1664973Generated: October 30, 2026

(4-Fluoro-phenyl)-(4-methyl-piperidin-4-yl)-methanone → HCID 178453897, compound

https://huagongshe.com/reaction/1664973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Fluoro-phenyl)-(4-methyl-piperidin-4-yl)-methanoneHCID 20530715—
ReactantHCID 178453902HCID 178453902—
ReactantHCID 178453924HCID 178453924—
ProductHCID 178453897HCID 178453897—

Reaction Steps

According to the procedure described for the synthesis of Trans-(4-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-cyclohexyl)-carbamic acid tert-butyl ester (intermediate E, example 1), the title compound was synthesized from (4-Fluoro-phenyl)-(4-methyl-piperidin-4-yl)-methanone and Trans-[4-(2-Oxo-ethyl)-cyclohexyl]-carbamic acid tert-butyl ester. MS (m/e): 447.4 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08039490B2
Source datasetuspto-grants-2011_10
ORD IDord-12ff893f94854978966fbe3a7fddd590
Source noteuspto-grants-2011_10