HRID1665023

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10556

Propane, 1-iodo-2-methyl-

C4H9I

HCID10796

Cesium carbonate

CCs2O3

结构：CS(=O)(=O)c1cccc(-c2ncc(CNS(=O)(=O)c3ccccc3Cl)s2)c1

HCID67439913

未命名化合物

PRODUCTS

生成物

结构：CC(C)CN(Cc1cnc(-c2cccc(S(C)(=O)=O)c2)s1)S(=O)(=O)c1ccccc1Cl

HCID25234387

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID31374

Dimethylacetamide

C4H9NO

PROCEDURE

实验过程

In analogy to example 10, step 3, 2-chloro-N-[2-(3-methanesulfonyl-phenyl)-thiazol-5-ylmethyl]-benzenesulfonamide (example 10, step 2) was reacted with 1-iodo-2-methylpropane and cesium carbonate in N,N-dimethylacetamide to give 2-chloro-N-isobutyl-N-[2-(3-methanesulfonyl-phenyl)-thiazol-5-ylmethyl]-benzenesulfonamide as a colorless solid. MS: 499.0 ([M+H]+)