HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → N-((5-Bromothiophen-2-yl)methyl)-2-methylpropan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | 5-Bromothiophene-2-carbaldehyde | HCID 78428 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-((5-Bromothiophen-2-yl)methyl)-2-methylpropan-1-amine | HCID 28428595 | — |
Reaction Steps
In analogy to example 13, step 1, 5-bromothiophene-2-carboxaldehyde was reacted with isobutylamine and sodium borohydride in methanol to give (5-bromo-thiophen-2-ylmethyl)-isobutyl-amine as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039493B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-0bcae63037d44136a6152554e54972df |
| Source note | uspto-grants-2011_10 |