HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 25235120, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Benzoic acid, 2-(chlorosulfonyl)-, methyl ester | HCID 117830 | — |
| Reactant | Isobutyl-[5-(3-methanesulfonyl-phenyl)-thiophen-2-ylmethyl]-amine | HCID 67441398 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 25235120 | HCID 25235120 | — |
Reaction Steps
In analogy to example 13, step 2, isobutyl-[5-(3-methanesulfonyl-phenyl)-thiophen-2-ylmethyl]-amine (example 15, step 2) was reacted with methyl-2-(chlorosulfonyl)-benzoate and N,N-diisopropyl ethyl amine in dichloromethane to give 2-{isobutyl-[5-(3-methanesulfonyl-phenyl)-thiophen-2-ylmethyl]-sulfamoyl}-benzoic acid methyl ester as a colorless oil. MS: 522.3 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039493B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-9165077e29bf4142b2cf607154b197a3 |
| Source note | uspto-grants-2011_10 |