HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 25234249, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-Bromoethyl methyl ether | HCID 80972 | — |
| Reactant | N-[5-(3-methanesulfonyl-phenyl)-thiophen-2-ylmethyl]-2-trifluoromethyl-benzenesulfonamide | HCID 67440497 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 25234249 | HCID 25234249 | — |
Reaction Steps
In analogy to example 10, step 3, N-[5-(3-methanesulfonyl-phenyl)-thiophen-2-ylmethyl]-2-trifluoromethyl-benzenesulfonamide (example 27, step 1) was reacted with 2-bromoethyl methyl ether and cesium carbonate in N,N-dimethylacetamide to give N-[5-(3-methanesulfonyl-phenyl)-thiophen-2-ylmethyl]-N-(2-methoxy-ethyl)-2-trifluoromethyl-benzenesulfonamide as a light yellow oil. MS: 550.8 ([M+NH4]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08039493B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-b0c4f68467c74bf2ba7060cf3b1fd452 |
| Source note | uspto-grants-2011_10 |