HRID1665236

反应详情

EQUATION

反应方程式

HRID 1665236 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

3-(4′,5′-Difluoro-2′-methoxy-biphenyl-4-yloxymethyl)-benzoic acid methyl ester (6.5 g, 16.92 mmol) and 2N KOH (33.84 mL, 67.68 mmol) in 100 mL MeOH were reacted as above to yield 6.1 g (97.4) of 3-(4′,5′-difluoro-2′-methoxy-biphenyl-4-yloxymethyl)-benzoic acid. LC-MS (ES) calculated for C21H16F2O4, 370.36; found m/z 369 [M−H]−.