HCID 57875821, compound → HCID 57875798, compound

Participants

Reaction Steps

10% Pd/C (80 mg) was added to a stirred solution of (4-benzyl-piperazin-1-yl)-(3,4,5-trifluoro-phenyl)-methanone (800 mg, 2.4 mmol) in methanol (20 mL) and the mixture was stirred under an atmosphere of hydrogen for 6 hours. The mixture was then filtered over celite and the filtrate concentrated to afford 600 mg (95%) of piperazin-1-yl-(3,4,5-trifluoro-phenyl)-methanone. LCMS: 245.09 (M+1)+, 92.4%

Provenance & Evidence