Bromide ion → 1-Cyclopropyl-2,2,2-trifluoro-1-(4-(4-(phenylsulfonyl)-1-piperazinyl)phenyl)ethanol
Reaction equation
[Br-:28].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH:29]1([Mg+:32])[CH2:30][CH2:31]1.[F:1][C:2]([C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8]([N:11]2[CH2:12][CH2:13][N:14]([S:17](=[O:18])(=[O:19])[c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH2:15][CH2:16]2)[cH:9][cH:10]1)([F:26])[F:27]>>[F:1][C:2]([C:3]([OH:4])([c:5]1[cH:6][cH:7][c:8]([N:11]2[CH2:12][CH2:13][N:14]([S:17](=[O:18])(=[O:19])[c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH2:15][CH2:16]2)[cH:9][cH:10]1)[CH:29]1[CH2:30][CH2:31]1)([F:26])[F:27]Participants
5
Sources & evidence
- ORD record
- ord-6434165f15d9422a8a049bf19734d35b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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