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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1665678Generated: November 1, 2026

4-Aminobiphenyl → Formamide, N-(1,1'-biphenyl)-4-yl-

https://huagongshe.com/reaction/1665678

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminobiphenylHCID 7102—
ReactantEthyl formateHCID 8025—
ProductFormamide, N-(1,1'-biphenyl)-4-yl-HCID 9568486.2%

Reaction Steps

A mixture of biphenyl-4-ylamine (100 mg, 0.59 mmol) and ethylformate (1 mL) was stirred at reflux temperature for 1 hr. After the completion of the reaction, the reaction mixture was quenched with cold water. The precipitate was filtered to afford 100 mg (86.2% Yield) of N-biphenyl-4-yl-formamide as the required product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08039463B2
Source datasetuspto-grants-2011_10
ORD IDord-830b7b86db6041399a8280fc346fdbba
Source noteuspto-grants-2011_10