Lithium Hydroxide → HCID 57508893, compound

HRID 1665938Notes

Reaction equation

C([O:3][C:4]([C:6]1[S:7][C:8]([S:19][CH3:20])=[C:9]2[CH2:14][C:13]([CH2:17][CH3:18])([CH2:15][CH3:16])[CH2:12][CH2:11][C:10]=12)=[O:5])C.[Li+].[OH-]>>[CH2:17]([C:13]1([CH2:15][CH3:16])[CH2:12][CH2:11][C:10]2=[C:6]([C:4]([OH:5])=[O:3])[S:7][C:8]([S:19][CH3:20])=[C:9]2[CH2:14]1)[CH3:18]

Participants

Reactant 2

HCID 3939Lithium Hydroxide

HCID 57508892HCID 57508892, compound

Product 1

HCID 57508893HCID 57508893, compound

Procedure

5,5-Diethyl-3-methylsulfanyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester is treated with LiOH as described in Example K to give 5,5-diethyl-3-methylsulfanyl-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid; LC-MS: tR=1.06 min, [M+1]=285.0; 1H NMR (CDCl3): δ 2.96 (t, J=6.4 Hz, 2H), 2.54 (s, 3H), 2.31 (s, 2H), 1.55 (t, J=6.4 Hz, 2H), 1.37-1.20 (m, 4H), 0.83 (t, J=7.3 HZ, 6H).

Sources & evidence

ORD record: ord-ee32827c394644cc93ef4a4ca864fd6c
Source dataset: uspto-grants-2011_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08039644B2

Reaction notes

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