HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 10137827, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 58928526 | HCID 58928526 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10137827 | HCID 10137827 | — |
Reaction Steps
3-[6-(2,2-Dimethyl-propylamino)-2-methylamino-pyrimidin-4-ylamino]-4,N-dimethyl-benzamide (35 mg), aq. sat. sodium bicarbonate (0.05 mL) and bromine (21 mg) were stirred in methylene chloride (1 mL) at room temperature for overnight. The product (4 mg) was purified with preparative thin layer chromatography. MS (m/z): 435 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08044040B2 |
| Source dataset | uspto-grants-2011_10 |
| ORD ID | ord-47e2ea1f5eeb4ba4b8f585ab71085516 |
| Source note | uspto-grants-2011_10 |