反应详情

A solution of [5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4,5-dihydro-1H-pyrazole-3-yl]methyl amine (19.33 g, 0.0545 mol) in diethylether (100 mL) and hydrogen chloride [2.0 M in diethyl ether (100 mL)] was stirred for 24 hours at room temperature and the solid formed was filtered off, washed with diethylether and dried to yield the [5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4,5-dihydro-1H-pyrazole-3-yl]methyl amine hydrochloride (19.41 g, 91%) as a yellow solid.

1. customthe solid formed
2. filtrationwas filtered off
3. washwashed with diethylether
4. customdried