Pyridine → Phenyl 6-chloropyrazin-2-ylcarbamate

Beteiligte Stoffe

Reaktionsschritte

A solution of 2-amino-6-chloropyrazine (2.0 g, 15.44 mmol) in a mix of 1:1 THF:MeCN (20 mL), and pyridine (1.28, 16.2 mmol) was treated dropwise with phenylchloroformate (2.54 g, 16.2 mmol) in THF (10 mL). After stirring for 18 h, the resulting solid was collected and dried to provide the title compound (2 g, 53%).

Herkunft & Nachweise